Clinical research on psychedelics, such as psilocybin (the psychoactive ingredient in certain types of mushrooms), has experienced a renaissance in the past two decades, leading to spectacular successes in treating conditions such as addiction (1), treatment-resistant depression (2), mood (3) and anxiety disorders or even end-of-life anxiety of cancer patients (4). But what about what Michael Pollan, author of “How to change your mind” (5), calls “the betterment of well people”? Could altered states of consciousness in general and psychedelics in particular be used to support the development and personal growth of healthy individuals, and could it even be used to catalyse leadership development?